SCLC Archetypes
Published in Cell Systems, 2022
Recommended citation: Groves SM, Ildefonso GV, McAtee CO, Ozawa PMM, Ireland AS, Stauffer PE, Wasdin PT, Huang X, Qiao Y, Lim JS, Bader J, Liu Q, Simmons AJ, Lau KS, Iams WT, Hardin DP, Saff EB, Holmes WR, Tyson DR, Lovly CM, Rathmell JC, Marth G, Sage J, Oliver TG, Weaver AM, Quaranta V. Archetype tasks link intratumoral heterogeneity to plasticity and cancer hallmarks in small cell lung cancer. Cell Syst. 2022; 13(9) 690-710.e17. doi:10.1016/j.cels.2022.07.006. PubMed PMID: 35981544. PMCID: PMC9615940. https://doi.org/10.1016/j.cels.2022.07.006
This paper describes the transcriptomics-defined archetypes found in small cell lung cancer, their enriched/selected phenotypes, and the relationship between the phenotypic heterogeneity and plasticity.
Groves SM, Ildefonso GV, McAtee CO, Ozawa PMM, Ireland AS, Stauffer PE, Wasdin PT, Huang X, Qiao Y, Lim JS, Bader J, Liu Q, Simmons AJ, Lau KS, Iams WT, Hardin DP, Saff EB, Holmes WR, Tyson DR, Lovly CM, Rathmell JC, Marth G, Sage J, Oliver TG, Weaver AM, Quaranta V. Archetype tasks link intratumoral heterogeneity to plasticity and cancer hallmarks in small cell lung cancer. Cell Syst. 2022; 13(9) 690-710.e17. doi:10.1016/j.cels.2022.07.006. PubMed PMID: 35981544. PMCID: PMC9615940.