Darren R. Tyson

Darren R. Tyson

Chicago boy, Cali-seasoned, mountain biker, mad scientist

Quantifying Drug Combination Synergy along Potency and Efficacy Axes

Published in Cell Systems, 2019

Recommended citation: Meyer CT, Wooten DJ, Paudel BB, Bauer J, Hardeman KN, Westover D, Lovly CM, Harris LA, Tyson DR, Quaranta V. Quantifying Drug Combination Synergy along Potency and Efficacy Axes. Cell Syst. 2019; 8(2) 97-108.e16. doi:10.1016/j.cels.2019.01.003. PubMed PMID: 30797775. PMCID: PMC6675406 https://doi.org/10.1016/j.cels.2019.01.003

This paper describes a quantitative framework and experimental approach for analyzing drug synergy that distinguishes drug efficacy from potency.

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Meyer CT, Wooten DJ, Paudel BB, Bauer J, Hardeman KN, Westover D, Lovly CM, Harris LA, Tyson DR, Quaranta V. Quantifying Drug Combination Synergy along Potency and Efficacy Axes. Cell Syst. 2019; 8(2) 97-108.e16. doi:10.1016/j.cels.2019.01.003. PubMed PMID: 30797775. PMCID: PMC6675406.